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Taurine Ameliorates Iron Overload-Induced Hepatocyte Injury via the Bcl-2/VDAC1-Mediated Mitochondrial Apoptosis Pathway

Iron overload can induce reactive oxygen species (ROS) burst and liver damage. Taurine can reduce ROS production and ameliorate liver injury caused by iron overload; however, the underlying molecular mechanism remains elusive. Herein, L02 cells treated with 120 μM iron dextran for 48 h showed marked...

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Detalles Bibliográficos
Autores principales: Feng, Xiaoyu, Hu, Wenfeng, Hong, Yujiao, Ruan, Linlin, Hu, Yueben, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308541/
https://www.ncbi.nlm.nih.gov/pubmed/35879990
http://dx.doi.org/10.1155/2022/4135752