Further Exploration of the Benzimidazole Scaffold as TRPC5 Inhibitors: Identification of 1‐Alkyl‐2‐(pyrrolidin‐1‐yl)‐1H‐benzo[d]imidazoles as Potent and Selective Inhibitors

The transient receptor potential cation channel 5 (TRPC5) plays an important role in numerous cellular processes. Due to this, it has gained considerable attention over the past few years as a potential therapeutic target. Recently, TRPC5 has been shown to be involved in the regulation of podocyte s...

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Detalles Bibliográficos
Autores principales: Sharma, Swagat, L. Pablo, Juan, Tolentino, Kirsten T., Gallegos, Wacey, Hinman, Jennifer, Beninato, Madison, Asche, MacKenzie, Greka, Anna, Hopkins, Corey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308755/
https://www.ncbi.nlm.nih.gov/pubmed/35557491
http://dx.doi.org/10.1002/cmdc.202200151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308755/
https://www.ncbi.nlm.nih.gov/pubmed/35557491
http://dx.doi.org/10.1002/cmdc.202200151

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