Structural basis of transposon end recognition explains central features of Tn7 transposition systems

Tn7 is a bacterial transposon with relatives containing element-encoded CRISPR-Cas systems mediating RNA-guided transposon insertion. Here, we present the 2.7 Å cryoelectron microscopy structure of prototypic Tn7 transposase TnsB interacting with the transposon end DNA. When TnsB interacts across re...

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Detalles Bibliográficos
Autores principales: Kaczmarska, Zuzanna, Czarnocki-Cieciura, Mariusz, Górecka-Minakowska, Karolina M., Wingo, Robert J., Jackiewicz, Justyna, Zajko, Weronika, Poznański, Jarosław T., Rawski, Michał, Grant, Timothy, Peters, Joseph E., Nowotny, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308760/
https://www.ncbi.nlm.nih.gov/pubmed/35654042
http://dx.doi.org/10.1016/j.molcel.2022.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308760/
https://www.ncbi.nlm.nih.gov/pubmed/35654042
http://dx.doi.org/10.1016/j.molcel.2022.05.005

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