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UPF1/circRPPH1/ATF3 feedback loop promotes the malignant phenotype and stemness of GSCs

Glioblastoma multiforme (GBM) is the most lethal type of craniocerebral gliomas. Glioma stem cells (GSCs) are fundamental reasons for the malignancy and recurrence of GBM. Revealing the critical mechanism within GSCs’ self-renewal ability is essential. Our study found a novel circular RNA (circRPPH1...

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Detalles Bibliográficos
Autores principales: Xu, Jinkun, Zhang, Guoqing, Hu, Jinpeng, Li, Hao, Zhao, Junshuang, Zong, Shengliang, Guo, Zhengting, Jiang, Yang, Jing, Zhitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308777/
https://www.ncbi.nlm.nih.gov/pubmed/35871061
http://dx.doi.org/10.1038/s41419-022-05102-2