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Human iPSC co-culture model to investigate the interaction between microglia and motor neurons

Motor neuron diseases such as amyotrophic lateral sclerosis are primarily characterized by motor neuron degeneration with additional involvement of non-neuronal cells, in particular, microglia. In previous work, we have established protocols for the differentiation of iPSC-derived spinal motor neuro...

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Detalles Bibliográficos
Autores principales: Vahsen, Björn F., Gray, Elizabeth, Candalija, Ana, Cramb, Kaitlyn M. L., Scaber, Jakub, Dafinca, Ruxandra, Katsikoudi, Antigoni, Xu, Yinyan, Farrimond, Lucy, Wade-Martins, Richard, James, William S., Turner, Martin R., Cowley, Sally A., Talbot, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308778/
https://www.ncbi.nlm.nih.gov/pubmed/35871163
http://dx.doi.org/10.1038/s41598-022-16896-8