Exosomal circPABPC1 promotes colorectal cancer liver metastases by regulating HMGA2 in the nucleus and BMP4/ADAM19 in the cytoplasm

Liver metastasis is the leading cause of death in colorectal carcinoma (CRC). However, little is known about the mechanisms of transferring effector messages between the primary tumor and the site of metastasis. Exosomes provide a novel transfer message method, and exosomal circular RNAs (circRNAs)...

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Detalles Bibliográficos
Autores principales: Li, Yang, Hu, Jialei, Wang, Meng, Yuan, Yihang, Zhou, Fangyuan, Zhao, Haosen, Qiu, Tianming, Liang, Leilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308786/
https://www.ncbi.nlm.nih.gov/pubmed/35871166
http://dx.doi.org/10.1038/s41420-022-01124-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308786/
https://www.ncbi.nlm.nih.gov/pubmed/35871166
http://dx.doi.org/10.1038/s41420-022-01124-z

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