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A polygenic score indexing a DRD2-related co-expression network is associated with striatal dopamine function

The D2 dopamine receptor (D2R) is the primary site of the therapeutic action of antipsychotics and is involved in essential brain functions relevant to schizophrenia, such as attention, memory, motivation, and emotion processing. Moreover, the gene coding for D2R (DRD2) has been associated with schi...

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Detalles Bibliográficos
Autores principales: D’Ambrosio, Enrico, Pergola, Giulio, Pardiñas, Antonio F., Dahoun, Tarik, Veronese, Mattia, Sportelli, Leonardo, Taurisano, Paolo, Griffiths, Kira, Jauhar, Sameer, Rogdaki, Maria, Bloomfield, Michael A. P., Froudist-Walsh, Sean, Bonoldi, Ilaria, Walters, James T. R., Blasi, Giuseppe, Bertolino, Alessandro, Howes, Oliver D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308811/
https://www.ncbi.nlm.nih.gov/pubmed/35871219
http://dx.doi.org/10.1038/s41598-022-16442-6