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Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector

In their GTP-bound (active) form, Rab proteins interact with effector proteins that control downstream signaling. One such Rab15 effector is Rep15, which is known to have a role in receptor recycling from the endocytic recycling compartment but otherwise remains poorly characterized. Here, we report...

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Detalles Bibliográficos
Autores principales: Rai, Amrita, Singh, Anurag K., Bleimling, Nathalie, Posern, Guido, Vetter, Ingrid R., Goody, Roger S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308819/
https://www.ncbi.nlm.nih.gov/pubmed/35871249
http://dx.doi.org/10.1038/s41467-022-31831-1