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Coimmunomodulation of tumor and tumor-draining lymph nodes during in situ vaccination promotes antitumor immunity
In situ vaccination has demonstrated the feasibility of priming local immunity for systemic antitumor responses. Although direct intratumoral (IT) delivery of adjuvant is the mainstay, tumor-draining lymph nodes (TDLNs) also play essential roles in antitumor immunity. We report that directing an adj...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309043/ https://www.ncbi.nlm.nih.gov/pubmed/35579961 http://dx.doi.org/10.1172/jci.insight.146608 |