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Coimmunomodulation of tumor and tumor-draining lymph nodes during in situ vaccination promotes antitumor immunity

In situ vaccination has demonstrated the feasibility of priming local immunity for systemic antitumor responses. Although direct intratumoral (IT) delivery of adjuvant is the mainstay, tumor-draining lymph nodes (TDLNs) also play essential roles in antitumor immunity. We report that directing an adj...

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Detalles Bibliográficos
Autores principales: Jeong, Moonkyoung, Kim, Heegon, Yoon, Junyong, Kim, Dong-Hyun, Park, Ji-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309043/
https://www.ncbi.nlm.nih.gov/pubmed/35579961
http://dx.doi.org/10.1172/jci.insight.146608