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Targeted gut microbiota manipulation attenuates seizures in a model of infantile spasms syndrome
Infantile spasms syndrome (IS) is a devastating early-onset epileptic encephalopathy associated with poor neurodevelopmental outcomes. When first-line treatment options, including adrenocorticotropic hormone and vigabatrin, are ineffective, the ketogenic diet (KD) is often employed to control seizur...
Autores principales: | Mu, Chunlong, Nikpoor, Naghmeh, Tompkins, Thomas A., Choudhary, Anamika, Wang, Melinda, Marks, Wendie N., Rho, Jong M., Scantlebury, Morris H., Shearer, Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309045/ https://www.ncbi.nlm.nih.gov/pubmed/35730569 http://dx.doi.org/10.1172/jci.insight.158521 |
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