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Bioactive extracellular vesicles from a subset of endothelial progenitor cells rescue retinal ischemia and neurodegeneration

Disruption of the neurovascular unit (NVU) underlies the pathophysiology of various CNS diseases. One strategy to repair NVU dysfunction uses stem/progenitor cells to provide trophic support to the NVU’s functionally coupled and interdependent vasculature and surrounding CNS parenchyma. A subset of...

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Detalles Bibliográficos
Autores principales: Marra, Kyle V., Aguilar, Edith, Wei, Guoqin, Usui-Ouchi, Ayumi, Ideguchi, Yoichiro, Sakimoto, Susumu, Friedlander, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309054/
https://www.ncbi.nlm.nih.gov/pubmed/35639473
http://dx.doi.org/10.1172/jci.insight.155928