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Bioactive extracellular vesicles from a subset of endothelial progenitor cells rescue retinal ischemia and neurodegeneration
Disruption of the neurovascular unit (NVU) underlies the pathophysiology of various CNS diseases. One strategy to repair NVU dysfunction uses stem/progenitor cells to provide trophic support to the NVU’s functionally coupled and interdependent vasculature and surrounding CNS parenchyma. A subset of...
Autores principales: | Marra, Kyle V., Aguilar, Edith, Wei, Guoqin, Usui-Ouchi, Ayumi, Ideguchi, Yoichiro, Sakimoto, Susumu, Friedlander, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309054/ https://www.ncbi.nlm.nih.gov/pubmed/35639473 http://dx.doi.org/10.1172/jci.insight.155928 |
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