Biological aging of CNS-resident cells alters the clinical course and immunopathology of autoimmune demyelinating disease

Biological aging is the strongest factor associated with the clinical phenotype of multiple sclerosis (MS). Relapsing-remitting MS typically presents in the third or fourth decade, whereas the mean age of presentation of progressive MS (PMS) is 45 years old. Here, we show that experimental autoimmun...

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Detalles Bibliográficos
Autores principales: Atkinson, Jeffrey R., Jerome, Andrew D., Sas, Andrew R., Munie, Ashley, Wang, Cankun, Ma, Anjun, Arnold, William D., Segal, Benjamin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309055/
https://www.ncbi.nlm.nih.gov/pubmed/35511417
http://dx.doi.org/10.1172/jci.insight.158153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309055/
https://www.ncbi.nlm.nih.gov/pubmed/35511417
http://dx.doi.org/10.1172/jci.insight.158153

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