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Biological aging of CNS-resident cells alters the clinical course and immunopathology of autoimmune demyelinating disease
Biological aging is the strongest factor associated with the clinical phenotype of multiple sclerosis (MS). Relapsing-remitting MS typically presents in the third or fourth decade, whereas the mean age of presentation of progressive MS (PMS) is 45 years old. Here, we show that experimental autoimmun...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309055/ https://www.ncbi.nlm.nih.gov/pubmed/35511417 http://dx.doi.org/10.1172/jci.insight.158153 |