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Intracellular ferritin heavy chain plays the key role in artesunate-induced ferroptosis in ovarian serous carcinoma cells

Artesunate, an antimalarial drug, induces ferroptosis, but the mechanism is still unclear. In the present study, we investigated how Artesunate induces ferroptosis in ovarian serous carcinoma. Experiments were performed using the ovarian serous carcinoma cell lines CaOV3 and SKOV3ip1, and the sensit...

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Detalles Bibliográficos
Autores principales: Koike, Tiger, Takenaka, Motoki, Suzuki, Noriko, Ueda, Yoko, Mori, Minako, Hirayama, Tasuku, Nagasawa, Hideko, Morishige, Ken-ichirou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309081/
https://www.ncbi.nlm.nih.gov/pubmed/35903602
http://dx.doi.org/10.3164/jcbn.21-82