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HDAC7 Activates IKK/NF-κB Signaling to Regulate Astrocyte-Mediated Inflammation

Class IIa histone deacetylases (HDAC) have been shown to drive innate immune cell-mediated inflammation in the peripheral system, but their roles in cerebral inflammatory responses remain largely unknown. Here, we elucidate that HDAC7 is selectively elevated in lipopolysaccharide (LPS)-challenged as...

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Detalles Bibliográficos
Autores principales: Ye, Jinwang, Zhong, Suyue, Deng, Yunsong, Yao, Xuanbao, Liu, Qiong, Wang, Jian-Zhi, Xiao, Shifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309093/
https://www.ncbi.nlm.nih.gov/pubmed/35871708
http://dx.doi.org/10.1007/s12035-022-02965-6