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GARP as a Therapeutic Target for the Modulation of Regulatory T Cells in Cancer and Autoimmunity

Regulatory T cells (Treg) play a critical role in immune homeostasis by suppressing several aspects of the immune response. Herein, Glycoprotein A repetitions predominant (GARP), the docking receptor for latent transforming growth factor (LTGF-β), which promotes its activation, plays a crucial role...

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Detalles Bibliográficos
Autores principales: Zimmer, Niklas, Trzeciak, Emily R., Graefen, Barbara, Satoh, Kazuki, Tuettenberg, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309211/
https://www.ncbi.nlm.nih.gov/pubmed/35898500
http://dx.doi.org/10.3389/fimmu.2022.928450