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GARP as a Therapeutic Target for the Modulation of Regulatory T Cells in Cancer and Autoimmunity
Regulatory T cells (Treg) play a critical role in immune homeostasis by suppressing several aspects of the immune response. Herein, Glycoprotein A repetitions predominant (GARP), the docking receptor for latent transforming growth factor (LTGF-β), which promotes its activation, plays a crucial role...
Autores principales: | Zimmer, Niklas, Trzeciak, Emily R., Graefen, Barbara, Satoh, Kazuki, Tuettenberg, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309211/ https://www.ncbi.nlm.nih.gov/pubmed/35898500 http://dx.doi.org/10.3389/fimmu.2022.928450 |
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