Optimized intramuscular immunization with VSV-vectored spike protein triggers a superior immune response to SARS-CoV-2

Immunization with vesicular stomatitis virus (VSV)-vectored COVID-19 vaccine candidates expressing the SARS-CoV-2 spike protein in place of the VSV glycoprotein relies implicitly on expression of the ACE2 receptor at the muscular injection site. Here, we report that such a viral vector vaccine did n...

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Detalles Bibliográficos
Autores principales: Taddeo, Adriano, Veiga, Inês Berenguer, Devisme, Christelle, Boss, Renate, Plattet, Philippe, Weigang, Sebastian, Kochs, Georg, Thiel, Volker, Benarafa, Charaf, Zimmer, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309237/
https://www.ncbi.nlm.nih.gov/pubmed/35879345
http://dx.doi.org/10.1038/s41541-022-00508-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309237/
https://www.ncbi.nlm.nih.gov/pubmed/35879345
http://dx.doi.org/10.1038/s41541-022-00508-7

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