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Adenosine Deaminase 2 Deficiency (DADA2): A Crosstalk Between Innate and Adaptive Immunity

Deficiency of Adenosine deaminase 2 (DADA2) is a monogenic autoinflammatory disorder presenting with a broad spectrum of clinical manifestations, including immunodeficiency, vasculopathy and hematologic disease. Biallelic mutations in ADA2 gene have been associated with a decreased ADA2 activity, le...

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Detalles Bibliográficos
Autores principales: Signa, Sara, Bertoni, Arinna, Penco, Federica, Caorsi, Roberta, Cafaro, Alessia, Cangemi, Giuliana, Volpi, Stefano, Gattorno, Marco, Schena, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309328/
https://www.ncbi.nlm.nih.gov/pubmed/35898506
http://dx.doi.org/10.3389/fimmu.2022.935957