Signal Peptide Features Determining the Substrate Specificities of Targeting and Translocation Components in Human ER Protein Import

In human cells, approximately 30% of all polypeptides enter the secretory pathway at the level of the endoplasmic reticulum (ER). This process involves cleavable amino-terminal signal peptides (SPs) or more or less amino-terminal transmembrane helices (TMHs), which serve as targeting determinants, a...

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Detalles Bibliográficos
Autores principales: Lang, Sven, Nguyen, Duy, Bhadra, Pratiti, Jung, Martin, Helms, Volkhard, Zimmermann, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309488/
https://www.ncbi.nlm.nih.gov/pubmed/35899032
http://dx.doi.org/10.3389/fphys.2022.833540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309488/
https://www.ncbi.nlm.nih.gov/pubmed/35899032
http://dx.doi.org/10.3389/fphys.2022.833540

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