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Signal Peptide Features Determining the Substrate Specificities of Targeting and Translocation Components in Human ER Protein Import
In human cells, approximately 30% of all polypeptides enter the secretory pathway at the level of the endoplasmic reticulum (ER). This process involves cleavable amino-terminal signal peptides (SPs) or more or less amino-terminal transmembrane helices (TMHs), which serve as targeting determinants, a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309488/ https://www.ncbi.nlm.nih.gov/pubmed/35899032 http://dx.doi.org/10.3389/fphys.2022.833540 |