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Dopamine Transporter Knockout Rats Show Impaired Wellbeing in a Multimodal Severity Assessment Approach

In preclinical psychiatry research, animals are central to modeling and understanding biological mechanisms of behavior and psychiatric disorders. We here present the first multimodal severity assessment of a genetically modified rat strain used in psychiatric research, lacking the dopamine transpor...

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Detalles Bibliográficos
Autores principales: Mallien, Anne Stephanie, Becker, Laura, Pfeiffer, Natascha, Terraneo, Federica, Hahn, Melissa, Middelman, Anthonieke, Palme, Rupert, Creutzberg, Kerstin Camile, Begni, Veronica, Riva, Marco Andrea, Leo, Damiana, Potschka, Heidrun, Fumagalli, Fabio, Homberg, Judith R., Gass, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309546/
https://www.ncbi.nlm.nih.gov/pubmed/35898652
http://dx.doi.org/10.3389/fnbeh.2022.924603