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Depletion of Foxp3(+) regulatory T cells augments CD4(+) T cell immune responses in atherosclerosis-prone hypercholesterolemic mice

Compelling evidence suggests a crucial role for Foxp3(+) regulatory T cells (Tregs) in the control of atherosclerosis. Although suppression of pro-inflammatory CD4(+) T cell immune responses is supposed to be important for athero-protective action of Foxp3(+) Tregs, few studies have provided direct...

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Detalles Bibliográficos
Autores principales: Kasahara, Kazuyuki, Sasaki, Naoto, Amin, Hilman Zulkifli, Tanaka, Toru, Horibe, Sayo, Yamashita, Tomoya, Hirata, Ken-ichi, Rikitake, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309665/
https://www.ncbi.nlm.nih.gov/pubmed/35898604
http://dx.doi.org/10.1016/j.heliyon.2022.e09981