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S-Ketamine Oral Thin Film—Part 1: Population Pharmacokinetics of S-Ketamine, S-Norketamine and S-Hydroxynorketamine

Ketamine is administered predominantly via the intravenous route for the various indications, including anesthesia, pain relief and treatment of depression. Here we report on the pharmacokinetics of sublingual and buccal fast-dissolving oral-thin-films that contain 50 mg of S-ketamine in a populatio...

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Detalles Bibliográficos
Autores principales: Simons, Pieter, Olofsen, Erik, van Velzen, Monique, van Lemmen, Maarten, Mooren, René, van Dasselaar, Tom, Mohr, Patrick, Hammes, Florian, van der Schrier, Rutger, Niesters, Marieke, Dahan, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309697/
https://www.ncbi.nlm.nih.gov/pubmed/35899184
http://dx.doi.org/10.3389/fpain.2022.946486