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β-Hydroxybutyrate Attenuates Painful Diabetic Neuropathy via Restoration of the Aquaporin-4 Polarity in the Spinal Glymphatic System

Waste removal is essential for maintaining homeostasis and the normal function of the central nervous system (CNS). The glymphatic system based on aquaporin-4 (AQP4) water channels on the endfeet of astrocytes is recently discovered as the excretion pathway for metabolic waste products of CNS. In th...

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Detalles Bibliográficos
Autores principales: Wang, Fei-xiang, Xu, Chi-liang, Su, Can, Li, Jiang, Lin, Jing-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309893/
https://www.ncbi.nlm.nih.gov/pubmed/35898407
http://dx.doi.org/10.3389/fnins.2022.926128