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When underlying biology threatens the randomization principle — initial gout flares of urate-lowering therapy
Flare is the dominant feature of gout and occurs because of inflammatory response to monosodium urate crystals; prevention of gout flares should be the major goal of gout care. However, a paradoxical increase in the risk of flare following initiation of urate-lowering therapy presents considerable c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309993/ https://www.ncbi.nlm.nih.gov/pubmed/35879610 http://dx.doi.org/10.1038/s41584-022-00804-5 |