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Case Report: Clinical and Serological Hallmarks of Cytokine Release Syndrome in a Canine B Cell Lymphoma Patient Treated With Autologous CAR-T Cells

BACKGROUND: Chimeric antigen receptor-T (CAR-T) cells have transformed the treatment of human B cell malignancies. With the advent of CAR-T therapy, specific and in some cases severe toxicities have been documented with cytokine release syndrome (CRS) being the most frequently reported. As dogs deve...

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Detalles Bibliográficos
Autores principales: Atherton, Matthew J., Rotolo, Antonia, Haran, Kumudhini P., Mason, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310037/
https://www.ncbi.nlm.nih.gov/pubmed/35898541
http://dx.doi.org/10.3389/fvets.2022.824982