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Hesperetin promotes longevity and delays aging via activation of Cisd2 in naturally aged mice

BACKGROUND: The human CISD2 gene is located within a longevity region mapped on chromosome 4q. In mice, Cisd2 levels decrease during natural aging and genetic studies have shown that a high level of Cisd2 prolongs mouse lifespan and healthspan. Here, we evaluate the feasibility of using a Cisd2 acti...

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Detalles Bibliográficos
Autores principales: Yeh, Chi-Hsiao, Shen, Zhao-Qing, Wang, Tai-Wen, Kao, Cheng-Heng, Teng, Yuan-Chi, Yeh, Teng-Kuang, Lu, Chung-Kuang, Tsai, Ting-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310407/
https://www.ncbi.nlm.nih.gov/pubmed/35871686
http://dx.doi.org/10.1186/s12929-022-00838-7