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Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes

OBJECTIVE: Linked metabolic and cardiovascular comorbidities are prevalent in hyperuricemia and gout. For mechanistic insight into impact on inflammatory processes and cardiometabolic risk factors of xanthine oxidase inhibitor urate-lowering therapy (ULT) titration to target, we performed a prospect...

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Detalles Bibliográficos
Autores principales: Guma, Monica, Dadpey, Benyamin, Coras, Roxana, Mikuls, Ted R., Hamilton, Bartlett, Quehenberger, Oswald, Thorisdottir, Hilda, Bittleman, David, Lauro, Kimberly, Reilly, Shannon M., Liu-Bryan, Ru, Terkeltaub, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310412/
https://www.ncbi.nlm.nih.gov/pubmed/35879786
http://dx.doi.org/10.1186/s13075-022-02852-4