Cargando…

Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches

BACKGROUND: The immune cell compartment of the mammalian brain changes dramatically and peripheral T cells infiltrate the brain parenchyma during normal aging. However, the mechanisms underlying age-related T cell infiltration in the central nervous system remain unclear. RESULTS: Chronic inflammati...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaotao, Wang, Rui, Chen, Haoran, Jin, Chenghao, Jin, Ziyang, Lu, Jianan, Xu, Liang, Lu, Yunrong, Zhang, Jianmin, Shi, Ligen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310471/
https://www.ncbi.nlm.nih.gov/pubmed/35879802
http://dx.doi.org/10.1186/s12979-022-00289-6