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Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches
BACKGROUND: The immune cell compartment of the mammalian brain changes dramatically and peripheral T cells infiltrate the brain parenchyma during normal aging. However, the mechanisms underlying age-related T cell infiltration in the central nervous system remain unclear. RESULTS: Chronic inflammati...
Autores principales: | Zhang, Xiaotao, Wang, Rui, Chen, Haoran, Jin, Chenghao, Jin, Ziyang, Lu, Jianan, Xu, Liang, Lu, Yunrong, Zhang, Jianmin, Shi, Ligen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310471/ https://www.ncbi.nlm.nih.gov/pubmed/35879802 http://dx.doi.org/10.1186/s12979-022-00289-6 |
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