Nonviral mcDNA-mediated bispecific CAR T cells kill tumor cells in an experimental mouse model of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and the adoptive immunotherapy of which is worth studying. CD133, a kind of cancer stem cell (CSC) antigen, together with glypican-3 (GPC3) has been proved to be highly expressed in HCC cells and both of them are...

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Detalles Bibliográficos
Autores principales: Wang, Hezhi, Wang, Xiaoxiao, Ye, Xueshuai, Ju, Yi, Cao, Nana, Wang, Shuqi, Cai, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310485/
https://www.ncbi.nlm.nih.gov/pubmed/35879685
http://dx.doi.org/10.1186/s12885-022-09861-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310485/
https://www.ncbi.nlm.nih.gov/pubmed/35879685
http://dx.doi.org/10.1186/s12885-022-09861-1

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