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Nonviral mcDNA-mediated bispecific CAR T cells kill tumor cells in an experimental mouse model of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and the adoptive immunotherapy of which is worth studying. CD133, a kind of cancer stem cell (CSC) antigen, together with glypican-3 (GPC3) has been proved to be highly expressed in HCC cells and both of them are...

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Detalles Bibliográficos
Autores principales:	Wang, Hezhi, Wang, Xiaoxiao, Ye, Xueshuai, Ju, Yi, Cao, Nana, Wang, Shuqi, Cai, Jianhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310485/ https://www.ncbi.nlm.nih.gov/pubmed/35879685 http://dx.doi.org/10.1186/s12885-022-09861-1

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