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A multiscale brain network model links Alzheimer’s disease-mediated neuronal hyperactivity to large-scale oscillatory slowing

BACKGROUND: Neuronal hyperexcitability and inhibitory interneuron dysfunction are frequently observed in preclinical animal models of Alzheimer’s disease (AD). This study investigates whether these microscale abnormalities explain characteristic large-scale magnetoencephalography (MEG) activity in h...

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Detalles Bibliográficos
Autores principales: van Nifterick, Anne M., Gouw, Alida A., van Kesteren, Ronald E., Scheltens, Philip, Stam, Cornelis J., de Haan, Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310500/
https://www.ncbi.nlm.nih.gov/pubmed/35879779
http://dx.doi.org/10.1186/s13195-022-01041-4