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HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART

People with HIV (PWH) on antiretroviral therapy (ART) experience elevated rates of neurological impairment, despite controlling for demographic factors and comorbidities, suggesting viral or neuroimmune etiologies for these deficits. Here, we apply multimodal and cross-compartmental single-cell anal...

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Detalles Bibliográficos
Autores principales: Farhadian, Shelli F., Lindenbaum, Ofir, Zhao, Jun, Corley, Michael J., Im, Yunju, Walsh, Hannah, Vecchio, Alyssa, Garcia-Milian, Rolando, Chiarella, Jennifer, Chintanaphol, Michelle, Calvi, Rachela, Wang, Guilin, Ndhlovu, Lishomwa C., Yoon, Jennifer, Trotta, Diane, Ma, Shuangge, Kluger, Yuval, Spudich, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310520/
https://www.ncbi.nlm.nih.gov/pubmed/35801589
http://dx.doi.org/10.1172/jci.insight.160267