Type I interferons and TGF-β cooperate to induce liver fibrosis during HIV-1 infection under antiretroviral therapy

Liver diseases have become a major comorbidity health concern for people living with HIV-1 (PLWH) treated with combination antiretroviral therapy (cART). To investigate if HIV-1 infection and cART interact to lead to liver diseases, humanized mice reconstituted with progenitor cells from human fetal...

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Detalles Bibliográficos
Autores principales: Ahodantin, James, Nio, Kouki, Funaki, Masaya, Zhai, Xuguang, Wilson, Eleanor, Kottilil, Shyamasundaran, Cheng, Liang, Li, Guangming, Su, Lishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310524/
https://www.ncbi.nlm.nih.gov/pubmed/35639478
http://dx.doi.org/10.1172/jci.insight.152738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310524/
https://www.ncbi.nlm.nih.gov/pubmed/35639478
http://dx.doi.org/10.1172/jci.insight.152738

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