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Mutations in the telomerase reverse transcriptase promoter and PIK3CA gene are common events in penile squamous cell carcinoma of Italian and Ugandan patients

Penile carcinoma develops either through human papillomavirus (HPV) related or unrelated carcinogenic pathways. Genetic alterations and nucleotide changes in coding regions (ie, TP53, CDKN2A, PIK3CA and NOTCH1) are main cancer driver events either in HPV positive or in HPV negative tumours. We inves...

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Detalles Bibliográficos
Autores principales: Starita, Noemy, Pezzuto, Francesca, Sarno, Sabrina, Losito, Nunzia Simona, Perdonà, Sisto, Buonaguro, Luigi, Buonaguro, Franco M., Tornesello, Maria Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310576/
https://www.ncbi.nlm.nih.gov/pubmed/35253909
http://dx.doi.org/10.1002/ijc.33990