Interaction of background Ca(2+) influx, sarcoplasmic reticulum threshold and heart failure in determining propensity for Ca(2+) waves in sheep heart

ABSTRACT: Ventricular arrhythmias can cause death in heart failure (HF). A trigger is the occurrence of Ca(2+) waves which activate a Na(+)‐Ca(2+) exchange (NCX) current, leading to delayed after‐depolarisations and triggered action potentials. Waves arise when sarcoplasmic reticulum (SR) Ca(2+) con...

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Detalles Bibliográficos
Autores principales: Hutchings, David C., Madders, George W. P., Niort, Barbara C., Bode, Elizabeth F., Waddell, Caitlin A., Woods, Lori S., Dibb, Katharine M., Eisner, David A., Trafford, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Cardiovascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310721/
https://www.ncbi.nlm.nih.gov/pubmed/35233776
http://dx.doi.org/10.1113/JP282168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310721/
https://www.ncbi.nlm.nih.gov/pubmed/35233776
http://dx.doi.org/10.1113/JP282168

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