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Sexual dimorphism: increased sterol excretion leads to hypocholesterolaemia in female hyperbilirubinaemic Gunn rats

ABSTRACT: Circulating bilirubin is associated with reduced serum cholesterol concentrations in humans and in hyperbilirubinaemic Gunn rats. However, mechanisms contributing to hypocholesterolaemia remain unknown. Therefore, this study aimed to investigate cholesterol synthesis, transport and excreti...

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Detalles Bibliográficos
Autores principales: Vidimce, Josif, Pillay, Johara, Ronda, Onne, Boon, Ai‐Ching, Pennell, Evan, Ashton, Kevin J., van Dijk, Theo H., Wagner, Karl‐Heinz, Verkade, Henkjan J., Bulmer, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310728/
https://www.ncbi.nlm.nih.gov/pubmed/35156712
http://dx.doi.org/10.1113/JP282395