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Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H(2)O(2)-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling

Age-related cataract (ARC) is one of the leading blinding eye diseases worldwide. Chronic oxidative stress and the apoptosis of human lens epithelial cells (HLECs) have been suggested to be the mechanism underlying cataract formation. Acetyl-11-keto-β-boswellic acid (AKBA) is a pentacyclic triterpen...

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Detalles Bibliográficos
Autores principales: Yang, Tianke, Lin, Xiaolei, Li, Hongzhe, Zhou, Xiyue, Fan, Fan, Yang, Jianing, Luo, Yi, Liu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310784/
https://www.ncbi.nlm.nih.gov/pubmed/35899124
http://dx.doi.org/10.3389/fphar.2022.927871