Alendronate modified mPEG-PLGA nano-micelle drug delivery system loaded with astragaloside has anti-osteoporotic effect in rats

Astragaloside (AS) has an anti-osteoporotic effect, but its poor water solubility and low bioavailability limit its application. In this study, a novel nano-carrier with bone targeting was prepared by modifying mPEG-PLGA with alendronate (AL) before incorporation into astragaloside nano-micelles (AS...

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Detalles Bibliográficos
Autores principales: Xi, Yanhai, Wang, Weiheng, Ma, Liang, Xu, Ning, Shi, Changgui, Xu, Guohua, He, Hailong, Pan, Wenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310824/
https://www.ncbi.nlm.nih.gov/pubmed/35869674
http://dx.doi.org/10.1080/10717544.2022.2086942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310824/
https://www.ncbi.nlm.nih.gov/pubmed/35869674
http://dx.doi.org/10.1080/10717544.2022.2086942

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