Mechanistic modelling of enzyme‐restoration effects of new recombinant liver‐targeted proteins in acute intermittent porphyria

BACKGROUND AND PURPOSE: Acute intermittent porphyria (AIP) is a rare disease caused by a genetic mutation in the hepatic activity of the porphobilinogen‐deaminase. We aimed to develop a mechanistic model of the enzymatic restoration effects of a novel therapy based on the administration of different...

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Detalles Bibliográficos
Autores principales: Vera‐Yunca, Diego, Córdoba, Karol M., Parra‐Guillen, Zinnia P., Jericó, Daniel, Fontanellas, Antonio, Trocóniz, Iñaki F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310908/
https://www.ncbi.nlm.nih.gov/pubmed/35170015
http://dx.doi.org/10.1111/bph.15821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310908/
https://www.ncbi.nlm.nih.gov/pubmed/35170015
http://dx.doi.org/10.1111/bph.15821

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