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Mechanistic modelling of enzyme‐restoration effects of new recombinant liver‐targeted proteins in acute intermittent porphyria

BACKGROUND AND PURPOSE: Acute intermittent porphyria (AIP) is a rare disease caused by a genetic mutation in the hepatic activity of the porphobilinogen‐deaminase. We aimed to develop a mechanistic model of the enzymatic restoration effects of a novel therapy based on the administration of different...

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Detalles Bibliográficos
Autores principales:	Vera‐Yunca, Diego, Córdoba, Karol M., Parra‐Guillen, Zinnia P., Jericó, Daniel, Fontanellas, Antonio, Trocóniz, Iñaki F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310908/ https://www.ncbi.nlm.nih.gov/pubmed/35170015 http://dx.doi.org/10.1111/bph.15821

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