Asymmetric Synthesis of Bicyclic Pyrazolidinones through Alkaloid‐Catalyzed [3+2]‐Cycloadditions of Ketenes and Azomethine Imines

A versatile asymmetric synthesis of bicyclic pyrazolidinones through alkaloid‐catalyzed formal [3+2]‐ and [3+2+2]‐cycloadditions of ketenes with azomethine imines is described. The methodology was found to be tolerant of ketene and a variety of monosubstituted ketenes (R=alkyl, OAc). The products we...

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Detalles Bibliográficos
Autores principales: Mondal, Mukulesh, Mitra, Shubhanjan, Twardy, Dylan J., Panda, Manashi, Wheeler, Kraig A., Kerrigan, Nessan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311188/
https://www.ncbi.nlm.nih.gov/pubmed/35175649
http://dx.doi.org/10.1002/chem.202104391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311188/
https://www.ncbi.nlm.nih.gov/pubmed/35175649
http://dx.doi.org/10.1002/chem.202104391

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