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Asymmetric Synthesis of Bicyclic Pyrazolidinones through Alkaloid‐Catalyzed [3+2]‐Cycloadditions of Ketenes and Azomethine Imines
A versatile asymmetric synthesis of bicyclic pyrazolidinones through alkaloid‐catalyzed formal [3+2]‐ and [3+2+2]‐cycloadditions of ketenes with azomethine imines is described. The methodology was found to be tolerant of ketene and a variety of monosubstituted ketenes (R=alkyl, OAc). The products we...
Autores principales: | Mondal, Mukulesh, Mitra, Shubhanjan, Twardy, Dylan J., Panda, Manashi, Wheeler, Kraig A., Kerrigan, Nessan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311188/ https://www.ncbi.nlm.nih.gov/pubmed/35175649 http://dx.doi.org/10.1002/chem.202104391 |
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