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Effect of molecular size on interstitial pharmacokinetics and tissue catabolism of antibodies

Advances in antibody engineering have enabled the construction of novel molecular formats in diverse shapes and sizes, providing new opportunities for biologic therapies and expanding the need to understand how various structural aspects affect their distribution properties. To assess the effect of...

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Detalles Bibliográficos
Autores principales: Rafidi, Hanine, Rajan, Sharmila, Urban, Konnie, Shatz-Binder, Whitney, Hui, Keliana, Ferl, Gregory Z., Kamath, Amrita V., Boswell, C. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311319/
https://www.ncbi.nlm.nih.gov/pubmed/35867780
http://dx.doi.org/10.1080/19420862.2022.2085535