Preventing Cholesterol-Induced Perk (Protein Kinase RNA-Like Endoplasmic Reticulum Kinase) Signaling in Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation

Vascular smooth muscle cells (SMCs) undergo complex phenotypic modulation with atherosclerotic plaque formation in hyperlipidemic mice, which is characterized by de-differentiation and heterogeneous increases in the expression of macrophage, fibroblast, osteogenic, and stem cell markers. An increase...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Abhijnan, Guan (关蒲骏), Pujun, Majumder, Suravi, Kaw, Kaveeta, Zhou (周桢), Zhen, Zhang, Chen, Prakash, Siddharth K., Kaw, Anita, Buja, L. Maximillian, Kwartler, Callie S., Milewicz, Dianna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311463/
https://www.ncbi.nlm.nih.gov/pubmed/35708026
http://dx.doi.org/10.1161/ATVBAHA.121.317451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311463/
https://www.ncbi.nlm.nih.gov/pubmed/35708026
http://dx.doi.org/10.1161/ATVBAHA.121.317451

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