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Upregulation of Thioredoxin Reductase 1 Expression by Flavan-3-Ols Protects Human Kidney Proximal Tubular Cells from Hypoxia-Induced Cell Death

Renal hypoxia and its associated oxidative stress is a common pathway for the development of kidney diseases, and using dietary antioxidants such as flavan-3-ols to prevent kidney failure has received much attention. This study investigates the molecular mechanism by which flavan-3-ols prevent hypox...

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Detalles Bibliográficos
Autores principales: Zhu, Jixiao, Fu, Manqin, Gao, Jian, Dai, Guoyu, Guan, Qiunong, Du, Caigan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311547/
https://www.ncbi.nlm.nih.gov/pubmed/35883890
http://dx.doi.org/10.3390/antiox11071399