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Protein Binding in Translational Antimicrobial Development-Focus on Interspecies Differences
Background/Introduction: Plasma protein binding (PPB) continues to be a key aspect of antibiotic development and clinical use. PPB is essential to understand several properties of drug candidates, including antimicrobial activity, drug-drug interaction, drug clearance, volume of distribution, and th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311574/ https://www.ncbi.nlm.nih.gov/pubmed/35884177 http://dx.doi.org/10.3390/antibiotics11070923 |