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Protein Binding in Translational Antimicrobial Development-Focus on Interspecies Differences

Background/Introduction: Plasma protein binding (PPB) continues to be a key aspect of antibiotic development and clinical use. PPB is essential to understand several properties of drug candidates, including antimicrobial activity, drug-drug interaction, drug clearance, volume of distribution, and th...

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Detalles Bibliográficos
Autores principales: Ahmed, Hifza, Bergmann, Felix, Zeitlinger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311574/
https://www.ncbi.nlm.nih.gov/pubmed/35884177
http://dx.doi.org/10.3390/antibiotics11070923